Heat Stability and Species Range of Purified Staphylococcal α-Toxin
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چکیده
منابع مشابه
Distinction between Pore Assembly by Staphylococcal α-Toxin versus Leukotoxins
The staphylococcal bipartite leukotoxins and the homoheptameric alpha-toxin belong to the same family of beta-barrel pore-forming toxins despite slight differences. In the alpha-toxin pore, the N-terminal extremity of each protomer interacts as a deployed latch with two consecutive protomers in the vicinity of the pore lumen. N-terminal extremities of leukotoxins as seen in their three-dimensio...
متن کاملHemolysis of Rabbit Erythrocytes by Purified Staphylococcal Alpha-toxin. I. Kinetics of the Lytic Reaction.
Cooper, Louis Z. (New England Center Hospital, Boston, Mass.), Morton A. Madoff, and Louis Weinstein. Hemolysis of rabbit erythrocytes by purified staphylococcal alpha-toxin: I. Kinetics of the lytic reaction. J. Bacteriol. 87:127-135. 1964.-The hemolytic activity of purified staphylococcal alpha-lysin was found to be directly proportional to toxin concentration and inversely related to the log...
متن کاملStaphylococcal enterotoxin B and α‑toxin induce the apoptosis of ECV304 cells via similar mechanisms.
Staphylococcal enterotoxin B (SEB) and α‑toxin produced by Staphylococcus aureus (S. aureus) are important in the pathogenesis of diseases. In the present study, we investigated the effects of SEB and α‑toxin on ECV304 cells. It was identified that both SEB and α‑toxin were capable of inducing the apoptosis of ECV304 cells in a dose‑ and time‑dependent manner. In addition, SEB and α‑toxin were ...
متن کاملToxoids of Pseudomonas aeruginosa exotoxin-A: photoaffinity inactivation of purified toxin and purified toxin derivatives.
For the preparation of greatly detoxified but highly immunogenic toxoids, two enzymatically active, low-toxicity derivatives of Pseudomonas aeruginosa exotoxin-A were further inactivated by photoaffinity labeling. These derivatives were formed during toxin purification, when a relatively crude toxin preparation was concentrated by ammonium sulfate precipitation and subsequently dialyzed. These ...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1966
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.91.5.1686-1692.1966